Preoperative monocyte count is a predictor of recurrence after Stage I lung adenocarcinoma resection.

ABSTRACT:

Objectives

High-grade tumours are observed even in Stage I lung adenocarcinomas. Tumour spread through air spaces (STAS) is a risk factor for recurrence after resection. However, there is no ideal predictive biomarker for STAS in high-grade Stage I lung adenocarcinoma. This study assessed the prognostic impact of the preoperative peripheral monocyte count in lung adenocarcinoma.

Methods

We retrospectively analysed the data of 444 patients with resected Stage I lung adenocarcinoma during 2006-2016. Univariable and multivariable Cox proportional analyses of recurrence-free probability (RFP) and overall survival (OS) were used to analyze preoperative complete peripheral blood cell count data. Since monocyte count was associated with poor prognosis, the relationship between preo

SUBMITTER: Yoshida C 

PROVIDER: S-EPMC9159418 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature