Bioprinted Gelatin-Recombinant Type III Collagen Hydrogel Promotes Wound Healing.

ABSTRACT: Artificial skins are biomaterials that can replace the lost skin or promote the regeneration of damaged skin. Skin regenerative biomaterials are highly applauded because they can exempt patients with severe burns from the painful procedure of autologous skin transplantation. Notwithstanding decades of research, biocompatible, degradable, and printable biomaterials that can effectively promote skin regeneration as a transplantation replacement in clinical use are still scarce. Here, we report one type of all-protein hydrogel material as the product of the enzymatic crosslinking reaction of gelatin and a recombinant type III collagen (rColIII) protein. Doping the rColIII protein in gelatin reduces the inflammatory response as an implant underneath the skin. The all-protein hydrogel can be bi

SUBMITTER: Huang J 

PROVIDER: S-EPMC9159484 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature