Conceptual and Analytical Overlap Between Allostatic Load and Systemic Biological Aging Measures: Analyses From the National Survey of Midlife Development in the United States.

ABSTRACT:

Background

Indices quantifying allostatic load (AL) and biological aging (BA) have independently received widespread use in epidemiological literature. However, little attention has been paid to their conceptual and quantitative overlap. By reviewing literature utilizing measures of AL and BA, and conducting comparative analysis, we highlight similarities and differences in biological markers employed and approach toward scale construction. Further, we outline opportunities where both types of indices might be improved by adopting methodological features of the other.

Methods

Using data from the National Survey of Midlife Development in the United States (N = 2055, age = 26-86), we constructed 3 AL indices: 1 common literature standard and 2 alternative formulations informed

SUBMITTER: Hastings WJ 

PROVIDER: S-EPMC9159656 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature