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Laser-ablative aqueous synthesis and characterization of elemental boron nanoparticles for biomedical applications.


ABSTRACT: Boron-based nano-formulations look very promising for biomedical applications, including photo- and boron neutron capture therapies, but the fabrication of non-toxic water-dispersible boron nanoparticles (NPs), which contain the highest boron atom concentration, is difficult using currently available chemical and plasma synthesis methods. Here, we demonstrate purely aqueous synthesis of clean boron NPs by methods of femtosecond laser ablation from a solid boron target in water, thus free of any toxic organic solvents, and characterize their properties. We show that despite highly oxidizing water ambience, the laser-ablative synthesis process follows an unusual scenario leading to the formation of boron NPs together with boric acid (H3BO3) as an oxidation by-product co

SUBMITTER: Pastukhov AI 

PROVIDER: S-EPMC9159993 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature