Dataset Information

Minimal invasive interlaminar approach for untethering of fatty filum terminale in pediatric patients - how I do it.

ABSTRACT:

Background

Fatty filum terminale is a form of spinal dysraphism and a third of all patients develop symptoms such as sensory, motor, and urinary impairment. Early surgery at 6 months has the advantage that the bone density is still soft, and the patients are not ambulatory yet, promoting faster healing.

Method

We present our minimal invasive surgical technique for FFT untethering.

Conclusion

Due to the low complication rate and the potentially high benefit of surgery, prophylactic untethering is recommended.

SUBMITTER: Greuter L

PROVIDER: S-EPMC9160132 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Minimal invasive interlaminar approach for untethering of fatty filum terminale in pediatric patients - how I do it.

Greuter Ladina L Licci Maria M Terrier Axel A Guzman Raphael R Soleman Jehuda J

Acta neurochirurgica 20220422 6

<h4>Background</h4>Fatty filum terminale is a form of spinal dysraphism and a third of all patients develop symptoms such as sensory, motor, and urinary impairment. Early surgery at 6 months has the advantage that the bone density is still soft, and the patients are not ambulatory yet, promoting faster healing.<h4>Method</h4>We present our minimal invasive surgical technique for FFT untethering.<h4>Conclusion</h4>Due to the low complication rate and the potentially high benefit of surgery, proph ...[more]

PMID: 35459966

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Project description:PurposePreoperative diagnosis of filum terminale ependymomas (FTEs) versus schwannomas is difficult but essential for surgical planning and prognostic assessment. With the advancement of deep-learning approaches based on convolutional neural networks (CNNs), the aim of this study was to determine whether CNN-based interpretation of magnetic resonance (MR) images of these two tumours could be achieved.MethodsContrast-enhanced MRI data from 50 patients with primary FTE and 50 schwannomas in the lumbosacral spinal canal were retrospectively collected and used as training and internal validation datasets. The diagnostic accuracy of MRI was determined by consistency with postoperative histopathological examination. T1-weighted (T1-WI), T2-weighted (T2-WI) and contrast-enhanced T1-weighted (CE-T1) MR images of the sagittal plane containing the tumour mass were selected for analysis. For each sequence, patient MRI data were randomly allocated to 5 groups that further underwent fivefold cross-validation to evaluate the diagnostic efficacy of the CNN models. An additional 34 pairs of cases were used as an external test dataset to validate the CNN classifiers.ResultsAfter comparing multiple backbone CNN models, we developed a diagnostic system using Inception-v3. In the external test dataset, the per-examination combined sensitivities were 0.78 (0.71-0.84, 95% CI) based on T1-weighted images, 0.79 (0.72-0.84, 95% CI) for T2-weighted images, 0.88 (0.83-0.92, 95% CI) for CE-T1 images, and 0.88 (0.83-0.92, 95% CI) for all weighted images. The combined specificities were 0.72 based on T1-WI (0.66-0.78, 95% CI), 0.84 (0.78-0.89, 95% CI) based on T2-WI, 0.74 (0.67-0.80, 95% CI) for CE-T1, and 0.81 (0.76-0.86, 95% CI) for all weighted images. After all three MRI modalities were merged, the receiver operating characteristic (ROC) curve was calculated, and the area under the curve (AUC) was 0.93, with an accuracy of 0.87.ConclusionsCNN based MRI analysis has the potential to accurately differentiate ependymomas from schwannomas in the lumbar segment.

Dataset Information

Minimal invasive interlaminar approach for untethering of fatty filum terminale in pediatric patients - how I do it.

Background

Method

Conclusion

Publications

Minimal invasive interlaminar approach for untethering of fatty filum terminale in pediatric patients - how I do it.

Similar Datasets

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