Aberrant Functional Network of Small-World in Sudden Sensorineural Hearing Loss With Tinnitus.

ABSTRACT: Few researchers investigated the topological properties and relationships with cognitive deficits in sudden sensorineural hearing loss (SNHL) with tinnitus. To explore the topological characteristics of the brain connectome following SNHL from the global level and nodal level, we recruited 36 bilateral SNHL patients with tinnitus and 37 well-matched healthy controls. Every subject underwent pure tone audiometry tests, neuropsychological assessments, and MRI scanning. AAL atlas was employed to divide a brain into 90 cortical and subcortical regions of interest, then investigated the global and nodal properties of "small world" network in SNHL and control groups using a graph-theory analysis. The global characteristics include small worldness, cluster coefficient, characteristic path length,

SUBMITTER: Hua JC 

PROVIDER: S-EPMC9160300 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature