The Psychopathology of Worthlessness in Depression.

ABSTRACT:

Background

Despite common dissatisfaction with the syndromic heterogeneity of major depression, investigations into its symptom structure are scarce. Self-worthlessness/inadequacy is a distinctive and consistent symptom of major depression across cultures.

Aims

We investigated whether self-worthlessness is associated with self-blaming attribution-related symptoms or is instead an expression of reduced positive feelings overall, as would be implied by reduced positive affect accounts of depression.

Methods

44,161 undergraduate students in Study 1, and 215 patients with current Major Depressive Disorder (MDD) and 237 age-matched healthy control participants in Study 2 completed the well-validated Symptom Check List-90. Depression-relevant items were used to construct re

SUBMITTER: Harrison P 

PROVIDER: S-EPMC9160466 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature