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Predictors of Extracapsular Spread in T1/T2 Oral Squamous Cell Carcinoma: A retrospective study.

ABSTRACT:

Introduction

In the N0 neck the incidence of ECS might range from 13 to 60%. In this retrospective study we intended at evaluating the primary tumor and nodal characteristics that might influence the presence of ECS in early stage OSCC.

Methods

The predictor variables were tumor and nodal features and the incidence of ENE was the outcome. Univariate and multivariate regression models along with ROC curve and Youden's J statistics was used for analysis. A p value < 0.05 was considered statistically significant.

Results

The cut off value for DOI was 6.5 mm and LN size was 12.5 mm with overall accuracy of 80.15% and 84.93% respectively. Primary tumor features and LN size was significantly associated with ENE.

Discussion

Oral tongue tumors and PNI are independent risk factors for ENE. An elective neck dissection remains the standard of care from both diagnostic and therapeutic viewpoints.

SUBMITTER: Tandon S

PROVIDER: S-EPMC9160750 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature

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Predictors of Extracapsular Spread in T1/T2 Oral Squamous Cell Carcinoma: A retrospective study.

Tandon Sapna S Bera Rathindra Nath RN Singh Akhilesh Kumar AK Mishra Madan M

Journal of oral biology and craniofacial research 20220527 4

<h4>Introduction</h4>In the N0 neck the incidence of ECS might range from 13 to 60%. In this retrospective study we intended at evaluating the primary tumor and nodal characteristics that might influence the presence of ECS in early stage OSCC.<h4>Methods</h4>The predictor variables were tumor and nodal features and the incidence of ENE was the outcome. Univariate and multivariate regression models along with ROC curve and Youden's J statistics was used for analysis. A p value < 0.05 was conside ...[more]

PMID: 35664955

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