Event-recurring multiband SWIFT functional MRI with 200-ms temporal resolution during deep brain stimulation and isoflurane-induced burst suppression in rat.

ABSTRACT:

Purpose

To develop a high temporal resolution functional MRI method for tracking repeating events in the brain.

Methods

We developed a novel functional MRI method using multiband sweep imaging with Fourier transformation (SWIFT), termed event-recurring SWIFT (EVER-SWIFT). The method is able to image similar repeating events with subsecond temporal resolution. Here, we demonstrate the use of EVER-SWIFT for detecting functional MRI responses during deep brain stimulation of the medial septal nucleus and during spontaneous isoflurane-induced burst suppression in the rat brain at 9.4 T with 200-ms temporal resolution.

Results

The EVER-SWIFT approach showed that the shapes and time-to-peak values of the response curves to deep brain stimulation significantly differed betwe

SUBMITTER: Paasonen E 

PROVIDER: S-EPMC9160777 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature