Assessment of Delayed Large Local Reactions After the First Dose of the SARS-CoV-2 mRNA-1273 Vaccine in Japan.

ABSTRACT:

Importance

A delayed large local reaction (DLLR) is a delayed-onset adverse skin reaction that may occur after injection of the mRNA-1273 vaccine against SARS-CoV-2.

Objective

To examine the associations between sex and age and susceptibility of DLLRs after mRNA-1273 vaccination.

Design, setting, and participants

This retrospective cross-sectional study was conducted at the Self-Defense Forces large-scale vaccination center in Tokyo, Japan, from May 24 to November 30, 2021. Participants were recipients of the second dose of the mRNA-1273 vaccine who had received the first dose 4 to 6 weeks earlier. Five experienced dermatologists interviewed participants to assess whether they had experienced symptoms of DLLR after administration of the first dose of the vaccine.

E

SUBMITTER: Higashino T 

PROVIDER: S-EPMC9161114 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature