Comparison of Two Waves of COVID-19 in Critically Ill Patients: A Retrospective Observational Study.

ABSTRACT:

Background

The SARS-CoV-2 virus caused the global COVID-19 pandemic, with waxing and waning course. This study was conducted to compare outcomes in the first two waves, in mechanically ventilated patients.

Methods

This retrospective observational study included all mechanically ventilated COVID-19 patients above 18 years of age, between March 2020 and January 2021. Patients were grouped into first wave from March 2020 to July 2020, and second wave from August 2020 to January 2021. Outcome measures were mortality, the development of acute kidney injury (AKI), and need for renal replacement therapy (RRT). Univariate and multivariate cox regression analysis were used to delineate risk factors for the outcome measures.

Results

A total of 426 patients, 285 in the first wav

SUBMITTER: Jana KR 

PROVIDER: S-EPMC9161135 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature