Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1N-(6-Methylpyridyl-2-methyl) Protecting Group.

ABSTRACT: 6-Methylpyridyl-2-methyl protected tetrazoles can be C-H deprotonated using the turbo-Grignard reagent and involved in the reactions with aldehydes and ketones. The protecting group can be cleaved under reductive electrochemical conditions using Pb bronze as a cathode and Zn as a sacrificial anode.

SUBMITTER: Grammatoglou K 

PROVIDER: S-EPMC9161418 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature