Toward Light-Controlled Supramolecular Peptide Dimerization.

ABSTRACT: The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor-ligand complex with cucurbit[8]uril into a homoternary FGG₂@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts.

SUBMITTER: Fernandes RJ 

PROVIDER: S-EPMC9161448 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature