Theta-burst stimulation entrains frequency-specific oscillatory responses.

ABSTRACT:

Background

Brain stimulation has emerged as a powerful tool in human neuroscience, becoming integral to next-generation psychiatric and neurologic therapeutics. Theta-burst stimulation (TBS), in which electrical pulses are delivered in rhythmic bouts of 3-8 Hz, seeks to recapitulate neural activity seen endogenously during cognitive tasks. A growing literature suggests that TBS can be used to alter or enhance cognitive processes, but little is known about how these stimulation events influence underlying neural activity.

Objective

Our study sought to investigate the effect of direct electrical TBS on mesoscale neural activity in humans by asking (1) whether TBS evokes persistent theta oscillations in cortical areas, (2) whether these oscillations occur at the stimulated freq

SUBMITTER: Solomon EA 

PROVIDER: S-EPMC9161680 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature