Framework Development for Clinical Comprehensive Evaluation of Drugs-a Study Protocol Using the Delphi Method and Analytic Hierarchy Process.

ABSTRACT: Measuring the value of drugs to help make health-care decisions is a complex process which involves confronting trade-offs among multiple objectives. Although guidelines have been released for clinical comprehensive evaluation of drugs, refinement is required when considering a specific drug used in a specific disease. In this study, a two-level framework for clinical comprehensive evaluation of drugs will be developed. Six first-level indicators, including safety, efficacy, costs/cost-effectiveness, novelty, suitability, and accessibility will be evaluated according to the Chinese Guideline for Clinical Comprehensive Evaluation of Drugs. The second-level components involved in the framework will be first validated by the Delphi method and subsequently compared with one another to get the

SUBMITTER: Zhang C 

PROVIDER: S-EPMC9161709 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature