Making genomic surveillance deliver: A lineage classification and nomenclature system to inform rabies elimination.

ABSTRACT: The availability of pathogen sequence data and use of genomic surveillance is rapidly increasing. Genomic tools and classification systems need updating to reflect this. Here, rabies virus is used as an example to showcase the potential value of updated genomic tools to enhance surveillance to better understand epidemiological dynamics and improve disease control. Previous studies have described the evolutionary history of rabies virus, however the resulting taxonomy lacks the definition necessary to identify incursions, lineage turnover and transmission routes at high resolution. Here we propose a lineage classification system based on the dynamic nomenclature used for SARS-CoV-2, defining a lineage by phylogenetic methods for tracking virus spread and comparing sequences across geographi

SUBMITTER: Campbell K 

PROVIDER: S-EPMC9162366 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature