Assessment of left and right ventricular functional parameters using dynamic dual-tracer [¹³N]NH3 and [¹⁸F]FDG PET/MRI.

ABSTRACT:

Background

Cardiac positron emission tomography/magnetic resonance imaging (PET/MRI) can assess various cardiovascular diseases. In this study, we intra-individually compared right (RV) and left ventricular (LV) parameters obtained from dual-tracer PET/MRI scan.

Methods

In 22 patients with coronary heart disease (69 ± 9 years) dynamic [¹³N]NH₃ (NH₃) and [¹⁸F]FDG (FDG) PET scans were acquired. The first 2 minutes were used to calculate LV and RV first-pass ejection fraction (FPEF). Additionally, LV end-systolic (LVESV) and end-diastolic (LVEDV) volume and ejection fraction (LVEF) were calculated from the early (EP) and late-myocardial phases (LP). MRI served as a reference.

Results

RVFPEF and LVFPEF from FDG and NH₃

SUBMITTER: Rasul S 

PROVIDER: S-EPMC9163002 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature