Fertility preservation in patients of childbearing age treated for breast cancer: A nationwide cohort study.

ABSTRACT:

Background

Approximately 7% of breast cancers are diagnosed in women under 40. Question of subsequent fertility has become fundamental. We aimed to evaluate the rate of fertility preservation (FP) by oocyte retrieval (OR) after ovarian stimulation in patients of childbearing age, managed for breast cancer with adjuvant chemotherapy in France, reuse rate of frozen gametes and live births rate (LBR) after treatment.

Methods

We included 15,774 women between 18 and 40 years old, managed by surgery and adjuvant chemotherapy for breast cancer, between January 2011 and December 2020 from a French health registry. Patients with OR after breast surgery and before chemotherapy were considered as FP group; those with no OR as no FP group. To compare LBR with French population independe

SUBMITTER: Duraes M 

PROVIDER: S-EPMC9163100 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature