CDCDB: A large and continuously updated drug combination database.

ABSTRACT: In recent years, due to the complementary action of drug combinations over mono-therapy, the multiple-drugs for multiple-targets paradigm has received increased attention to treat bacterial infections and complex diseases. Although new drug combinations screening has benefited from experimental tests like automated high throughput screening, it is limited due to the large number of possible drug combinations. The task of drug combination screening can be streamlined through computational methods and models. Such models require up-to-date databases; however, existing databases are static and consist of the data collected at the time of their creation. This paper introduces the Continuous Drug Combination Database (CDCDB), a continuously updated drug combination database. The CDCDB includes

SUBMITTER: Shtar G 

PROVIDER: S-EPMC9163158 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature