Urinary phenols and parabens in relation to hearing loss: The National Health and Nutrition Examination Survey.

ABSTRACT:

Introduction

The animal studies raise concerns about the possible ototoxicity of phenolic chemicals. Therefore, we conducted an epidemiologic study to examine the associations of phenols and parabens with hearing impairment.

Materials and methods

Bisphenol A (BPA), benzophenone-3 (BP-3), and triclosan (TCS) were measured in urine samples in the National Health and Nutrition Examination Survey (NHANES) 2003-06 and 2009-12. Methyl paraben (MPB) and propyl paraben (PPB) were measured in urine samples in NHANES 2005-06 and 2009-12. Hearing impairment was defined as a hearing threshold of more than 25 dB at each hearing frequency in the better ear. Tests for linear trend were conducted using the median concentrations of urinary phenols or parabens in each quartile as a continuous

SUBMITTER: Li MC 

PROVIDER: S-EPMC9163259 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature