Cluster Analysis Revealed Two Hidden Phenotypes of Cluster Headache.

ABSTRACT:

Objective

To investigate the possible subgroups of patients with Cluster Headache (CH) by using K-means cluster analysis.

Methods

A total of 209 individuals (mean (SD) age: 39.8 (11.3) years), diagnosed with CH by headache experts, participated in this cross-sectional multi-center study. All patients completed a semi-structured survey either face to face, preferably, or through phone interviews with a physician. The survey was composed of questions that addressed sociodemographic characteristics as well as detailed clinical features and treatment experiences.

Results

Cluster analysis revealed two subgroups. Cluster one patients (n = 81) had younger age at diagnosis (31.04 (9.68) vs. 35.05 (11.02) years; p = 0.009), a higher number of autonomic symptoms (

SUBMITTER: Yalinay Dikmen P 

PROVIDER: S-EPMC9163308 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature