Lipoprotein(a) and Cardiovascular Outcomes in Patients With Coronary Artery Disease and Different Metabolic Phenotypes.

ABSTRACT:

Background

The positive relationship between metabolic healthy obesity (MHO) and cardiovascular risk has been under debate in recent years. Previously, strong evidence supported the causal role of increased plasma lipoprotein(a) [Lp(a)] levels in cardiovascular disease (CVD). The current study aimed to investigate the different associations of Lp(a) and cardiovascular events (CVEs) in patients with coronary artery disease (CAD) and different metabolic phenotypes.

Methods

A total of 5,089 patients who were angiography-proven CAD were consecutively included and followed up for CVEs. Obesity was defined as a body mass index (BMI) ≥25 kg/m² according to Asia-specific BMI criteria. Patients were divided into four groups according to metabolic phenotypes, namely metabol

SUBMITTER: Jin JL 

PROVIDER: S-EPMC9163309 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature