Poor ovarian response is associated with air pollutants: A multicentre study in China.

ABSTRACT:

Background

Human evidence on the association between air pollution and ovarian response is scarce. Poor ovarian response (POR) with an incidence of 5-35% is a tricky problem in IVF treatment.

Methods

In this large-scale multicentre study, we included 2186 women with POR (< 4 oocytes retrieved) and 7033 women with a normal ovarian response (10-15 oocytes retrieved), who underwent their first in vitro fertilization treatment in five cities in northern China during 2015-2020. Average concentrations of six air pollutants (PM_2.5, PM₁₀, O₃, NO₂, CO, and SO₂) during different exposure windows (5 days, 1, 3, 6, and 12 months) before oocyte pick up (OPU) were calculated using data from the air monitoring station nearest to the re

SUBMITTER: Wu S 

PROVIDER: S-EPMC9163489 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature