Associations of handgrip strength with morbidity and all-cause mortality of cardiometabolic multimorbidity.

ABSTRACT:

Background

Cardiometabolic multimorbidity (CM) is an increasing public health and clinical concern. However, predictors for the development and prognosis of CM are poorly understood. The aims of this study were to investigate the relation between handgrip strength (HGS) and the risk of CM and to examine the association of HGS with all-cause mortality risk among patients with CM.

Methods

This prospective cohort study involved 493,774 participants from the UK Biobank. CM was defined as the simultaneous occurrence of two or more of the following conditions: type 2 diabetes, stroke, and coronary heart disease (CHD). Cox proportional hazards models were performed to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs).

Results

During a median follow-up of 12

SUBMITTER: Lu Y 

PROVIDER: S-EPMC9164350 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature