Establishment of MELD-lactate clearance scoring system in predicting death risk of critically ill cirrhotic patients.

ABSTRACT:

Background

To develop a scoring system related to the lactate clearance (ΔLA) to predict the mortality risk (MELD-ΔLA) for critically ill cirrhotic patients.

Methods

In this retrospective cohort study, 881 critically ill cirrhotic patients from the Medical Information Mart for Intensive Care (MIMIC-III) database were included eventually. The outcomes of our study were defined as ICU death, 28-day, 90-day and 1-year mortality. Predictors were identified by multivariate Cox analysis to develop the predictive scoring system. The C-index and area under the curve (AUC) of receiver operator characteristic curve (ROC) were used to identify the predicting performance of the MELD-ΔLA, sequential organ failure assessment (SOFA), chronic liver failure-sequential organ failure assessmen

SUBMITTER: Li X 

PROVIDER: S-EPMC9164412 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature