Chronic kidney disease and clinical outcomes in patients with COVID-19 in Japan.

ABSTRACT:

Background

Identifying predictive factors for coronavirus disease 2019 (COVID-19) is crucial for risk stratification and intervention. Kidney dysfunction contributes to the severity of various infectious diseases. However, the association between on-admission kidney dysfunction and the clinical outcome in COVID-19 patients is unclear.

Methods

This study was a multicenter retrospective observational cohort study of COVID-19 patients, diagnosed by polymerase chain reaction. We retrospectively analyzed 500 COVID-19 patients (mean age: 51 ± 19 years) admitted to eight hospitals in Japan. Kidney dysfunction was defined as a reduced estimated glomerular filtration rate (< 60 mL/min/1.73 m²) or proteinuria (≥ 1 + dipstick proteinuria) on admission. The primary composite

SUBMITTER: Sato R 

PROVIDER: S-EPMC9164570 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature