Diagnostic accuracy of [¹⁸F]PSMA-1007 PET/CT in biochemical recurrence of prostate cancer.

ABSTRACT:

Aim

Despite increasing use for the detection of biochemically recurrent prostate cancer (rPC), the diagnostic accuracy of positron emission tomography/computed tomography (PET/CT) with [¹⁸F]PSMA-1007 remains only partially investigated. The aim of this study was to determine the sensitivity (SE), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV) for PC-local recurrence and metastases on a per region basis.

Materials and methods

One hundred seventy-seven consecutive patients undergoing [¹⁸F]PSMA-1007 PET/CT for rPC were retrospectively analysed. Six body regions were defined: prostate fossa, pelvic lymph nodes (LN), retroperitoneal LN, supradiaphragmatic LN, bones, and soft tissue. A region was counted positive if at

SUBMITTER: Mingels C 

PROVIDER: S-EPMC9165245 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature