Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2.

ABSTRACT:

Background

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provides natural immunity against reinfection. Recent studies have shown waning of the immunity provided by the BNT162b2 vaccine. The time course of natural and hybrid immunity is unknown.

Methods

Using the Israeli Ministry of Health database, we extracted data for August and September 2021, when the B.1.617.2 (delta) variant was predominant, on all persons who had been previously infected with SARS-CoV-2 or who had received coronavirus 2019 vaccine. We used Poisson regression with adjustment for confounding factors to compare the rates of infection as a function of time since the last immunity-conferring event.

Results

The number of cases of SARS-CoV-2 infection per 100,000 person-

SUBMITTER: Goldberg Y 

PROVIDER: S-EPMC9165562 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature