Chronic snus use in healthy males alters endothelial function and increases arterial stiffness.

ABSTRACT:

Background

Snus usage is commonly touted as a safer alternative to cigarette smoking. However, recent studies have demonstrated possible adverse cardiovascular effects in chronic snus users. The present study evaluates the effects of chronic snus use on vascular function by assessing central arterial stiffness and endothelial vasodilatory function in healthy chronic snus users as compared to matched non-users.

Methods and results

Fifty healthy males (24 snus users, 26 age-matched controls) with a mean age of 44 years were included in the study. Arterial stiffness was assessed employing both pulse wave velocity and pulse wave analysis. Endothelial vasodilatory function was measured by venous occlusion plethysmography, utilizing intra-arterial administration of acetylcholine,

SUBMITTER: Antoniewicz L 

PROVIDER: S-EPMC9165771 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature