Cost-effectiveness analysis of patent foramen ovale closure versus medical therapy alone after cryptogenic stroke.

ABSTRACT:

Background

Closure of a patent foramen ovale reduces the risk of recurrent stroke compared with medical therapy alone in young patients with cryptogenic strokes revealed by randomized control trials. Some cost-effectiveness analyses outside Japan have shown that patent foramen ovale closure is cost-effective, but no studies have examined cost-effectiveness in Japan. The objective of this study is to assess cost-effectiveness, from the perspective of a Japanese healthcare payer, of patent foramen ovale closure versus medical therapy alone for patients with patent foramen ovale related to cryptogenic strokes.

Methods

A cost-effectiveness study was conducted by developing a decision tree and a Markov model. Probabilities and a 5.9-year time horizon followed the RESPECT study. U

SUBMITTER: Shijoh Y 

PROVIDER: S-EPMC9165785 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature