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Heart rate variability in hypothyroid patients: A systematic review and meta-analysis.


ABSTRACT:

Introduction

Hypothyroidism may be associated with changes in the autonomic regulation of the cardiovascular system, which may have clinical implications.

Objective

To conduct a systematic review and meta-analysis on the impact of hypothyroidism on HRV.

Materials and methods

PubMed, Cochrane, Embase and Google Scholar were searched until 20 August 2021 for articles reporting HRV parameters in untreated hypothyroidism and healthy controls. Random-effects meta-analysis were stratified by degree of hypothyroidism for each HRV parameters: RR intervals (or normal to normal-NN intervals), SDNN (standard deviation of RR intervals), RMSSD (square root of the mean difference of successive RR intervals), pNN50 (percentage of RR intervals with >50ms variation), total power (TP),

SUBMITTER: Brusseau V 

PROVIDER: S-EPMC9165841 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature