Identification of cardiovascular and molecular prognostic factors for the morbidity and mortality in COVID-19-sepsis (ICROVID): Protocol for a prospective multi-centre cohort study.

ABSTRACT:

Introduction

Severe COVID-19 constitutes a form of viral sepsis. Part of the specific pathophysiological pattern of this condition is the occurrence of cardiovascular events. These include pulmonary embolism, arrhythmias and cardiomyopathy as manifestations of extra-pulmonary organ dysfunction. Hitherto, the prognostic impact of these cardiovascular events and their predisposing risk factors remains unclear. This study aims to explore this question in two cohorts of viral sepsis-COVID-19 and influenza-in order to identify new theragnostic strategies to improve the short- and long-term outcome of these two diseases.

Methods and analysis

In this prospective multi-centre cohort study, clinical assessment will take place during the acute and post-acute phase of sepsis and be com

SUBMITTER: Neu C 

PROVIDER: S-EPMC9165863 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature