Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.

ABSTRACT:

Context

Immune system dysfunction is poorly represented in pediatric organ dysfunction definitions.

Objective

To evaluate evidence for criteria that define immune system dysfunction in critically ill children and associations with adverse outcomes and develop consensus criteria for the diagnosis of immune system dysfunction in critically ill children.

Data sources

We conducted electronic searches of PubMed and Embase from January 1992 to January 2020, using medical subject heading terms and text words to define immune system dysfunction and outcomes of interest.

Study selection

Studies of critically ill children with an abnormality in leukocyte numbers or function that is currently measurable in the clinical laboratory in which researchers assessed patient-cent

SUBMITTER: Hall MW 

PROVIDER: S-EPMC9166150 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature