Effects of rainfall on human leptospirosis in Thailand: evidence of multi-province study using distributed lag non-linear model.

ABSTRACT: Leptospirosis is a zoonotic bacterial disease that remains an important public health problem, especially in tropical developing countries. Many previous studies in Thailand have revealed the outbreak of human leptospirosis after heavy rainfall, but research determining its quantitative risks associated with rainfall, especially at the national level, remains limited. This study aims to examine the association between rainfall and human leptospirosis across 60 provinces of Thailand. A quasi-Poisson regression framework combined with the distributed lag non-linear model was used to estimate province-specific association between rainfall and human leptospirosis, adjusting for potential confounders. Province-specific estimates were then pooled to derive regional and national estimates using r

SUBMITTER: Phosri A 

PROVIDER: S-EPMC9167037 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature