Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats.

ABSTRACT:

Background

A considerable amount of attention has been recently paid to the discovery of effective natural antidiabetic drugs. Terminalia chebula is considered as the mother of herbs, with reported antidiabetic activity. This study aims to evaluate the renal and hepatic protective profile of its antidiabetic therapeutic doses.

Methods

To achieve the aim of the study, a total of 66 adult male rats of Sprague-Dawley species weighing about 180-200 g (weighed using a digital scale) were used. Type 2 diabetes mellitus (T2DM) was induced in using streptozotocin (STZ), rats were given a 5% dextrose solution for the next 24 h. Subjects received oral treatment of Terminalia chebula ethanolic extract at different doses (200, 400, and 600 mg/kg body weight) for 28 days. Measurements of

SUBMITTER: Eltimamy M 

PROVIDER: S-EPMC9167356 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature