PaO₂ / FiO₂ ratio responsiveness to prone positioning in intubated patients with severe COVID-19: a retrospective observational study.

ABSTRACT:

Aim

Prone positioning of coronavirus disease 2019 (COVID-19) patients could improve oxygenation. However, clinical data on prone positioning of intubated COVID-19 patients are limited. We investigated trends of PaO₂ / FiO₂ ratio values in patients during prone positioning to identify a predictive factor for early detection of patients requiring advanced therapeutic intervention such as extracorporeal membrane oxygenation (ECMO).

Methods

This retrospective, observational cohort study was undertaken between April 2020 and May 2021 in a tertiary referral hospital for COVID-19 in Osaka, Japan. We included intubated adult COVID-19 patients treated with prone positioning within the first 72 h of admission to the intensive care unit and followed them until hos

SUBMITTER: Kawakami A 

PROVIDER: S-EPMC9167425 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature