Impact of delayed processing of positive blood cultures on organism detection: a prospective multi-centre study.

ABSTRACT:

Background

Blood cultures remain the gold standard investigation for the diagnosis of bloodstream infections. In many locations, quality-assured processing of positive blood cultures is not possible. One solution is to incubate blood cultures locally, and then transport bottles that flag positive to a central reference laboratory for organism identification and antimicrobial susceptibility testing. However, the impact of delay between the bottle flagging positive and subsequent sub-culture on the viability of the isolate has received little attention.

Methods

This study evaluated the impact of delays to sub-culture (22 h to seven days) in three different temperature conditions (2-8 °C, 22-27 °C and 35 ± 2 °C) for bottles that had flagged positive in automated detection syste

SUBMITTER: Roberts T 

PROVIDER: S-EPMC9167519 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature