Transcriptomic analysis provides insights into molecular mechanisms of thermal physiology.

ABSTRACT: Physiological trait variation underlies health, responses to global climate change, and ecological performance. Yet, most physiological traits are complex, and we have little understanding of the genes and genomic architectures that define their variation. To provide insight into the genetic architecture of physiological processes, we related physiological traits to heart and brain mRNA expression using a weighted gene co-expression network analysis. mRNA expression was used to explain variation in six physiological traits (whole animal metabolism (WAM), critical thermal maximum (CT_max), and four substrate specific cardiac metabolic rates (CaM)) under 12 °C and 28 °C acclimation conditions. Notably, the physiological trait variations among the three geographically close (within

SUBMITTER: Drown MK 

PROVIDER: S-EPMC9167525 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature