The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis.

ABSTRACT:

Background

Preeclampsia is a multifactorial cardiovascular disorder of pregnancy. If left untreated, it can lead to severe maternal and fetal outcomes. Hence, timely diagnosis and management of preeclampsia are extremely important. Biomarkers of oxidative stress are associated with the pathogenesis of preeclampsia and therefore could be indicative of evolving preeclampsia and utilized for timely diagnosis. In this study, we conducted a systematic review and meta-analysis to determine the most reliable oxidative stress biomarkers in preeclampsia, based on their diagnostic sensitivities and specificities as well as their positive and negative predictive values.

Methods

A systematic search using PubMed, ScienceDirect, ResearchGate, and PLOS databases (1900 to March 2021) identi

SUBMITTER: Afrose D 

PROVIDER: S-EPMC9167545 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature