Variability in urinary concentrations of primary aromatic amines.

ABSTRACT: Despite their known carcinogenic potential, primary aromatic amines (AAs) continue to be used in various consumer products. Human exposure to AAs is a subject of current concern. Although urinary measurements are used in the assessment of exposure, little is known about within- and between-individual temporal variability in urinary concentrations of AAs. In this study, we determined the concentrations of 30 AAs, nicotine and cotinine in 213 first morning void (FMV) urine samples collected longitudinally for over a five-week period from 15 participants residing in the Albany area of New York State, USA. Eight AAs, namely, aniline, 2-naphthylamine (2-NA), p-cresidine (p-CD), p-toluidine (p-TD), o/m-toluidine (o/m-TD), 4-chloroaniline (4-CA), 4,4'-methylenedi-o-toluidine (4,4'-MDA), and 2,6-d

SUBMITTER: Chinthakindi S 

PROVIDER: S-EPMC9167796 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature