Analysis of the landscape of human enhancer sequences in biological databases.

ABSTRACT: The process of gene regulation extends as a network in which both genetic sequences and proteins are involved. The levels of regulation and the mechanisms involved are multiple. Transcription is the main control mechanism for most genes, being the downstream steps responsible for refining the transcription patterns. In turn, gene transcription is mainly controlled by regulatory events that occur at promoters and enhancers. Several studies are focused on analyzing the contribution of enhancers in the development of diseases and their possible use as therapeutic targets. The study of regulatory elements has advanced rapidly in recent years with the development and use of next generation sequencing techniques. All this information has generated a large volume of information that has been tran

SUBMITTER: Mulero Hernandez J 

PROVIDER: S-EPMC9168495 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature