The relation of common inflammatory cytokines with anxiety and depression and their values in estimating cardiovascular outcomes in coronary heart disease patients.

ABSTRACT:

Background

Inflammatory cytokines are associated with the occurrence and severity of psychological disorders in cerebro-cardiovascular disease patients. This study aimed to investigate the correlation of inflammatory cytokines with anxiety and depression in coronary heart disease (CHD) patients and their values for estimating cardiovascular outcomes.

Methods

Totally, 150 CHD patients and 50 healthy subjects were enrolled. Then, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, IL-10, and IL-17 in their serum samples were detected using ELISA assay; anxiety and depression were assessed by the HADS score. For CHD patients, major adverse cardiac events (MACE) were recorded and evaluated.

Results

CHD patients presented with increased TNF-α (median: 50.0 vs. 37.0 p

SUBMITTER: Lu H 

PROVIDER: S-EPMC9169184 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature