PHYTOCHROME-INTERACTING FACTORs trigger environmentally responsive chromatin dynamics in plants.

ABSTRACT: The interplay between light receptors and PHYTOCHROME-INTERACTING FACTORs (PIFs) serves as a regulatory hub that perceives and integrates environmental cues into transcriptional networks of plants^1,2. Although occupancy of the histone variant H2A.Z and acetylation of histone H3 have emerged as regulators of environmentally responsive gene networks, how these epigenomic features interface with PIF activity is poorly understood^3-7. By taking advantage of rapid and reversible light-mediated manipulation of PIF7 subnuclear localization and phosphorylation, we simultaneously assayed the DNA-binding properties of PIF7, as well as its impact on chromatin dynamics genome wide. We found that PIFs act rapidly to reshape the H2A.Z and H3K9ac epigenetic landscape in response to a

SUBMITTER: Willige BC 

PROVIDER: S-EPMC9169284 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature