Comparative Analysis of Gene Expression Patterns for Oral Epithelial Cell Functions in Periodontitis.

ABSTRACT: The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants in providing warning signals to the host immune and inflammatory cells and in communicating various detailed information on the noxious challenge to help drive specificity in the characteristics of the host response related to health or pathologic inflammation. Rhesus monkeys were used in these studies to evaluate the gingival transcriptome for naturally occurring disease samples (GeneChip® Rhesus Macaque Genome Array) or for ligature-induced disease (GeneChip® Rhesus Gene 1.0 ST Array) to explore up to 452 annotated genes related to epithelial

SUBMITTER: Gonzalez OA 

PROVIDER: S-EPMC9169451 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature