Use of mucoactive agents in cystic fibrosis: A consensus survey of Italian specialists.

ABSTRACT:

Background

The goal of mucoactive therapies in cystic fibrosis (CF) is to enhance sputum clearance and to reduce a progressive decline in lung function over the patient's lifetime. We aimed to investigate the level of consensus among specialists from Italian CF Centers on appropriateness of therapeutic use of dornase alfa (rhDNase) for CF patients.

Method

A consensus on appropriate prescribing in CF mucoactive agents was appraised by an online Delphi method, based on a panel of 27 pulmonologists, coordinated by a Scientific Committee of six experts in medical care of patients with CF.

Results

Full or very high consensus was reached on several issues related to therapeutic use of dornase alfa for CF patients in clinical practice.

Conclusions

The consensus reache

SUBMITTER: Volpi S 

PROVIDER: S-EPMC9169509 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature