Fast growth can counteract antibiotic susceptibility in shaping microbial community resilience to antibiotics.

ABSTRACT: Microbial communities often face external perturbations that can induce lasting changes in their composition and functions. Our understanding of how multispecies communities respond to perturbations such as antibiotics is limited, with susceptibility assays performed on individual, isolated species our primary guide in predicting community transitions. Here, we studied how bacterial growth dynamics can overcome differences in antibiotic susceptibility in determining community resilience: the recovery of the original community state following antibiotic exposure. We used an experimental community containing Corynebacterium ammoniagenes and Lactobacillus plantarum that displays two alternative stable states as a result of mutual inhibition. Although C. ammoniagenes was more susceptible to ch

SUBMITTER: Amor DR 

PROVIDER: S-EPMC9169654 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature