Cerebral White Matter Mediation of Age-Related Differences in Picture Naming Across Adulthood.

ABSTRACT: As people age, one of the most common complaints is difficulty with word retrieval. A wealth of behavioral research confirms such age-related language production deficits, yet the structural neural differences that relate to age-related language production deficits remains an open area of exploration. Therefore, the present study used a large sample of healthy adults across adulthood to investigate how age-related white matter differences in three key left-hemisphere language tracts may contribute to age-related differences in language ability. Specifically, we used diffusion tensor imaging to measure fractional anisotropy (FA) and radial diffusivity (RD) which are indicators of white matter structure. We then used a series of path models to test whether white matter from the superior long

SUBMITTER: Troutman SBW 

PROVIDER: S-EPMC9169883 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature