Negative and Positive Psychosocial Factors in Relation to Cognitive Health in Older African Americans.

ABSTRACT:

Background and objectives

Identifying potential intervention strategies to reduce cognitive decline, particularly among older African Americans at high risk for Alzheimer's dementia, is critical. This study aimed to investigate whether depressive symptoms, purpose in life, and their interrelations are associated with cognitive decline in older African Americans.

Research design and methods

We included older African Americans from the Minority Aging Research Study (n = 748) and Rush Memory and Aging Project (n = 109), without dementia at baseline. We assessed associations of depressive symptoms, purpose in life, and their interrelations, with baseline levels and change in global cognition using linear mixed-effects models.

Results

At baseline, each unit i

SUBMITTER: Wagner M 

PROVIDER: S-EPMC9169895 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature