Hypertension and retinal microvascular dysfunction (HyperVasc): protocol of a randomised controlled exercise trial in patients with hypertension.

ABSTRACT:

Introduction

Hypertension is a global healthcare burden that affects the structure and function of the macrocirculation and microcirculation and induces disease-specific end-organ damage. Vascular biomarkers are essential to timely diagnose this end-organ damage to improve cardiovascular (CV) risk stratification and medical decision making. Exercise therapy is an effective means to improve vascular health and reduce overall CV risk. However, it is still not clear whether high-intensity interval training (HIIT) is recommendable for patients with hypertension to reduce blood pressure, increase cardiorespiratory fitness and ameliorate vascular health.

Methods and analysis

The 'Hypertension and retinal microvascular dysfunction' trial will investigate macrovascular and microvasc

SUBMITTER: Streese L 

PROVIDER: S-EPMC9171229 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature