Early intubation and patient-centered outcomes in septic shock: a secondary analysis of a prospective multicenter study.

ABSTRACT:

Purpose

Despite the benefits of mechanical ventilation, its use in critically ill patients is associated with complications and had led to the growth of noninvasive techniques. We assessed the effect of early intubation (first 8 h after vasopressor start) in septic shock patients, as compared to non-early intubated subjects (unexposed), regarding in-hospital mortality, intensive care and hospital length of stay.

Methods

This study involves secondary analysis of a multicenter prospective study. To adjust for baseline differences in potential confounders, propensity score matching was carried out. In-hospital mortality was analyzed in a time-to-event fashion, while length of stay was assessed as a median difference using bootstrapping.

Results

A total of 735 patients (1

SUBMITTER: Mellado-Artigas R 

PROVIDER: S-EPMC9171484 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature